I just received my uBiome report for a sample taken 6 days after a sudden onset ME flare. It was sudden onset because over 15 minutes I could feel my entire body shift and booked off sick for the rest of that day (and following week). The cause was stress, the cause of 40% of ME cases according to studies (the other 60% were infections).
I have two normal health ubiome for reference (each at least 6 months apart). As you can see with this first chart, three important groups did a nose dive.
This is repeated with other groups:
Other items are unchanged, such as diversity
And looking at various levels of bacteria, nothing jumps out
Microbiome Site Analysis
I uploaded the JSON to
http://microbiomeprescription.com/upload , and then look at various reports.
What shows up in the comparison is that High Counts across all conditions went up by 30%.
Some specific jumps:
In terms of the experimental End Produces, we also see some interesting shifts (most numbers were roughly the same)
Large drops in following genus (was normal-range earlier and often went down to -98%)
- Akkermansia
- Anaerococcus
- Dialister
- Enterobacter
- Porphyromonas
- Staphylococcus
- Succiniclasticum
Major increases in following genus:
Bottom Line
First item is that this is likely a unique report — 6 days after onset. A diagnosis of ME/CFS classically requires 6 months of extensive no-results testing, so any ubiome test result would be after a significant progression of microbiome shifts.
Lactic acid producers has crashed, histamine and hydrogen peroxide producers have increased. Significant shift towards a IBS/IBD profile.
Probiotics
After preparing this post, I started with Enterogermina (4 Bacillus clausii in suspension) and within 12 hours found significant changes including:
- Stopping high frequency stool movements that had been ongoing for 4 days
- Change of mood – from borderline depression to very mellow and very very laid back.
It was interesting to note the list of avoid
Plans going forward (reduce the high ones)
- berberine (unfortunately if decrease one high, and increases the other — but it is the only substance know to reduce thalassospira)
- melatonin supplement
- mastic gum (prebiotic)
One of the items, choline deficiency, means that I should cut out my usual 2 eggs each morning because they are high in choline.
Some of the strong avoids were interesting (and unexpected)
CFS Remission 